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The Latest Breaking News from The Guardian - UK

Novo Nordisk bids $9bn for obesity drug maker Metsera in challenge to Pfizer

US biotech viewed as lucrative target partly because of its promising pipeline of weight-loss drugs

The Guardian - UK

Crystal Palace face five games in 11 days after Carabao Cup progress

Crystal Palace are facing the prospect of having to play five matches in 11 days during December after reaching the Carabao Cup quarter-finals

The Guardian - UK

Ministers to delegate some public appointments in attempt to cut delays

Under shake-up affecting about 4,000 roles, officials will run more of hiring process but ministers can have final say

The Guardian - UK

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Wendy & Peter Pan review – sugar-rush spectacle with an awfully big hormonal hot-crush

The RSC production of Ella Hickson’s feminist take on JM Barrie’s tale has grown into quite the theatrical monster, big on lights, waves and clashing cutlasses

The Guardian - UK

‘Morrisons killed us’: Britain’s most westerly mainland village shop closes after half a century

The Ferry Stores, in the remote village of Kilchoan, will shut its doors after struggling to fight off the decline in footfall and the advent of home delivery services

The Guardian - UK

Prayers for a Hungry Ghost review – a monster take on family trauma

Elisabeth Gunawan’s mythological horror blends puppetry, dance, theatre and film to explore the effects of a family’s relocation from Hong Kong to the US

The Guardian - UK

Rob Jetten: anti-Wilders, ‘yes we can’ candidate poised to be next Dutch PM

As liberal-progressive D66 party makes huge gains in election, former junior athlete with ‘positive story’ and ‘vision’ leads race for power

The Guardian - UK

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Lebanese president orders army to confront Israeli incursions after deadly raid

IDF says it was attacking Hezbollah infrastructure when it fired at a ‘suspect’ and the incident is under review

The Guardian - UK

Doctor Who lives on! But who will be the new Time Lord – and is it goodbye to Russell T Davies?

The BBC have confirmed that the long-running sci-fi show will return to our screens. But with ratings falling and its Disney partnership ending, questions hang over its future

The Guardian - UK

‘Tom Cruise was not happy’: Colin Farrell was so drunk on Minority Report he needed 46 takes for a single line

The Irish actor has revealed that his energetic birthday celebrations caused problems on the set of Spielberg’s 2002 film

The Guardian - UK

Killer Colin Pitchfork has plea for release from prison rejected

Pitchfork was jailed in 1988 for rape and murder of two teenage girls, Lynda Mann and Dawn Ashworth

The Guardian - UK

Yvonne Brewster obituary

Theatre director and founder of Talawa, the company that champions writers and actors of African and Caribbean heritage

The Guardian - UK

ECB keeps interest rates on hold despite eurozone inflation fears

Key deposit rate kept at 2% even as recovery starts to drive up price growth across bloc

The Guardian - UK

Volkswagen indicates shortage of Chinese chips would hit profits

New EV models are offsetting a slump in demand but Europe’s carmakers are bracing for shutdowns

The Guardian - UK

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news in one place.

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The Guardian - UK

First Thing: Trump says rare earths deal and tariff cut agreed with China

Overall US tariffs on Chinese goods will be lowered to 47% after talks. Plus: the far right loses support in Dutch election

The Guardian - UK

Max Dowman’s journey from Billericay to making history with Arsenal

How Arsenal-supporting family put the youngster on road to history-making appearance at Emirates on Wednesday

The Guardian - UK

Warming whites? Break away from the ice bucket this winter

As the nights draw in, there’s no reason that the season’s bold, ripe, room-temperature wines need only be red …

The Guardian - UK

The least frightening films ever – ranked!

A Halloween screening doesn’t have to mean being scared witless. From serene sushi-making to a shell with shoes on, we run down the finest films for those of a nervous disposition

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The Guardian - UK

The luxury effect: why you’ll find more wildlife in wealthy areas – and what it means for your health

The discovery that affluent neighbourhoods have more diversity of nature has implications for human wellbeing – and sheds light on the structural injustices in cities

The Guardian - UK

Selling the left’s message in the digital age is an art – Ireland’s new president mastered it

From Mamdani-style visual branding to basketball clips, Catherine Connolly found her audience and spoke in a language they understood, says journalist Una Mullally

The Guardian - UK

Wayne McGregor review: shimmering dance spectacular without a live dancer in sight

Installations, some triggered by the viewer’s own body, show off the wide range of a choreographer always fizzing with fresh ideas

The Guardian - UK

How deprived is your area? Look up your postcode as new data for England released

New data ranks every area of England against a set of metrics for deprivation. Find out where yours figures in the statistics

The Guardian - UK

‘She called me a silly boy! Lovely lady!’ Your treasured memories of Prunella Scales

From her assistance with crosswords to a wink that set a career in motion, Guardian readers share favourite memories of the actor

The Guardian - UK

Birmingham city council was probably never bankrupt, says accountancy expert

Declaration in 2023 that led to spending cuts was based on underestimation of reserves of more than £1bn, shows fresh analysis

The Guardian - UK

Xi-Trump meeting: America has discovered that bullies can be bullied back

Outcome appears closer to truce than durable peace but outline of broader diplomatic relationship is visible

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