U.S. President Donald Trump took to Truth Social on Wednesday, July 1, to share one of his strangest AI-generated videos yet, portraying himself as a doctor diagnosing a group of celebrities with Trump Derangement Syndrome (TDS).
Those featured in the video were Whoopi Goldberg, Robert De Niro, Julia Roberts, Rosie O’Donnell, Edward Norton, and John Leguizamo—all outspoken critics of him.
Trump not only diagnosed the stars with the fictitious mental health condition but also prescribed a series of tongue-in-cheek treatments, making the video all the more deviant.
One of the suggested remedies was: “Have a Diet Coke like me, and you’re gonna see a remarkable difference in your life.”
Trump’s new AI-generated video showed him playing a doctor who treats his outspoken celebrity critics for imaginary TDS
Trump Derangement Syndrome is an adaptation of Bush Derangement Syndrome, which was coined by columnist Charles Krauthammer in 2003.
Krauthammer described the term as “the acute onset of paranoia in otherwise normal people in reaction to the politics, the presidency—nay—the very existence of George W. Bush.”
“Have you or someone you know been diagnosed with TDS?” the AI-generated Trump asked at the start of the clip he posted.
“The symptoms can be relentless. Fortunately, I’m Doctor Trump, and I have a treatment plan.”
Trump then invited viewers to hear from some of his patients.
“I couldn’t eat, I couldn’t sleep, constantly angry…” the fake De Niro said. “I made everyone miserable around me.”
Roberts added, “I feel like I’ve aged 20 years in the last two years,” further claiming she was starting to “worry” about her future.
O’Donnell noted that she has been “suffering for over a decade,” while Goldberg said she believed she was a “lost cause.”
Similar claims were made by the remaining stars as well.
— Donald J. Trump (@realDonaldTrump) July 2, 2026
De Niro famously branded Trump as an “existential threat to our freedoms and security” this March.
O’Donnell and Trump, meanwhile, have been locked in a public feud since 2006 and have repeatedly blasted each other in the press.
Goldberg, for her part, accused Trump of wanting to be a totalitarian for life before the 2024 presidential election, and Roberts narrated a video for Vote Common Good at the same time, reminding women that their votes were independent of their husbands’.
Her video showed a woman voting for Trump’s opponent, Democratic candidate Kamala Harris.
Trump’s satirical video concluded with him recommending “turning off fake news” and “saying your prayers,” in addition to sipping Diet Coke as the cure for the fictional TDS.
The video sparked rapid criticism of Donald Trump across social media platforms
“Is there a Nobel prize for thin-skinned presidents?” one asked, while another recalled, “Presidents used to act like adults back in the day.”
“So childish,” a third said in agreement.
“Instead of working, he is busy doing cartoons,” alleged a fourth.
“Maybe if he put as much time and effort into actual presidential tasks, he’d be doing something to benefit America,” a fifth remarked.
“God, this cannot be over soon enough,” a separate user prayed.
Several others defended the celebrities featured in the video, arguing that Trump, not them, was the one with mental health issues.
“A man with narcissistic personality disorder is diagnosing other people as deranged,” one wrote, while another commented, “Every accusation is a confession.”
Trump has appeared as Jesus Christ, the Pope, Superman, and other characters in earlier AI-generated content
Trump’s depiction as Jesus Christ came on April 12 to mark Orthodox Easter. He was shown in the post as healing a sick man.
The president later told reporters that he thought the post showed him as a doctor, not Jesus.
The image of Trump dressed as the Pope was shared on May 2, 2025. The timing is important here, as this occurred shortly after the demise of Pope Francis on April 21 and just days before Catholic cardinals were set to begin the papal conclave to elect a successor.
Before posting the picture, Trump had joked that he would “like to be pope,” calling himself the “number one choice” for the position.
An image of Trump photoshopped as Superman was shared by White House social media accounts on July 10 of the same year to ride the pop culture wave of director James Gunn’s new Superman movie, which premiered in theaters the following morning.
In other notable AI-generated content, Donald Trump made himself part of Mount Rushmore alongside George Washington, Thomas Jefferson, Theodore Roosevelt, and Abraham Lincoln, and also played the Greek mythological character Atlas.
“Celebrities should sure,” a netizen said in reference to Trump’s AI video