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The Latest Breaking News from Clinical Trial

From the lab to clinical trials – why a preventative lung cancer vaccine could soon be a reality

It’s the third most common cancer in the UK, causing tens of thousands of deaths annually. But what if the disease, often only diagnosed when it’s too late, could be stopped before it even begins?

The Guardian - UK

Pfizer and Valneva's Lyme disease vaccine shows 70% efficacy in clinical trial

Pfizer and Valneva's Lyme disease vaccine has shown promising results in clinical trials, paving the way for regulatory approval despite setbacks due to fewer cases than expected, according to the companies.

Euronews

Masked T-cell engagers: cancer immunotherapies for the future?

A new immunotherapy drug has demonstrated early promise in a recent prostate cancer clinical trial. The drug, called VIR-5500, is a “masked T-cell engager”. This type of immunotherapy ignites our own immune arsenal to fight cancer.

The Conversation

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'It could revolutionize, completely, the way we treat depression': Researchers are exploring promising immune therapy for treating psychiatric symptoms

Live Science spoke with the scientists behind an upcoming clinical trial testing an immune therapy for depression.

LiveScience

UK health official recused from puberty blockers trial after bias claims

MHRA says Prof Jacob George will no longer be involved after gender-critical social media posts from last year

The Guardian - UK

New prostate cancer drug showing ‘remarkable’ results during clinical trial

The new drug, known as VIR-5500, uses a so-called cloaking device and only activates when it reaches the tumour

The Independent UK

‘A miracle baby’: Newborn Hugo rewrites medical history after groundbreaking womb transplant

A tiny baby named Hugo has quietly made medical history in the UK. And yet, at its heart, this isn’t really a story about science. It’s about a mother who finally got to hold the child she once believed she would never have. Hugo was born just before Christmas 2025…

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New oral pill beats previous alternatives and shows 8% weight loss in clinical trials

Eli Lilly’s new oral pill, orforglipron, led to up to 8% weight loss in clinical trials, outperforming existing oral semaglutide alternatives.

Euronews

UK clinical trial into puberty blockers on hold after medicines regulator steps in

Recruitment of children for study delayed after MHRA warns that participants should be no younger than 14

The Guardian - UK

Grail Stock Is Deeply Oversold on Cancer Test Failings. Is There Any Hope Left to Buy the Dip?

Grail stock crashed on Friday after its NHS-Galleri clinical trial failed to meet primary endpoint. Here’s why investors are cautioned against treating GRAL shares as a bargain.

Barchart

Clinical trial into puberty blockers paused after ‘new concerns’ from medicines regulator

The MHRA will now discuss the concerns, related to the wellbeing of children and young people with gender dysphoria, with trial sponsor King’s College London next week

The Independent UK

Clinical trial into puberty blockers paused after ‘new concerns’ from regulator

It comes after legal action was launched against the Government after campaigners including Harry Potter author JK Rowling expressed their opposition

Evening Standard

Stroke victim with just one rare symptom highlights unusual signs of condition

Gordon Robb, a former vice-president of a biotech company, is taking part in a new British Heart Foundation-funded clinical trial.

The Independent UK

Clinical Trials Show Moderna's New mRNA Flu Vaccine Is Safe and Effective. FDA Won't Even Consider It.

An overzealous government agency suppresses medical innovation yet again.

Reason

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Fortune

Sanofi CEO: The enterprise AI shift will reshape pharma in 2026

At Sanofi, AI has shifted from experimentation to becoming a vital part of our infrastructure.

Evening Standard

Wes Streeting ‘not comfortable’ with puberty blocker clinical trial

The Health Secretary made a ban on puberty blockers indefinite in December last year.

Evening Standard

Innovative therapy gives hope to patients whose blood cancer ‘seemed incurable’

Almost two thirds of patients with T-cell acute lymphoblastic leukaemia involved in a clinical trial of the treatment are now disease-free.

Benzinga

Kymera Stock Smashes 52-Week High As New Pill Crushes Eczema Markers

Kymera Therapeutics, Inc. (NASDAQ:KYMR) on Monday released clinical results from the BroADen Phase 1b atopic dermatitis (AD) clinical trial of KT-621, its oral STAT6 degrader medicine.

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Benzinga

What's Up With The Jump In Viking Therapeutics Stock?

Viking Therapeutics Inc (NASDAQ:VKTX) shares are trading higher on Thursday. The clinical-stage biopharmaceutical company seems to be benefitting from wider excitement in the obesity treatment area, as well as recent positive momentum after major clinical trial developments.

The Independent UK

‘Next generation’ treatment to cure leukaemia given NHS approval

‘The biggest thing it offers is hope,’ says patient involved in clinical trial which cured cancer in significant portion of leukaemia sufferers

The Guardian - UK

Two UK clinical trials to assess impact of puberty blockers in young people

Multi-year studies announced after Cass review found ‘insufficient evidence’ about effects on children with gender dysphoria

Axios

NIH cuts impacted 74,000 clinical trial patients: study

The termination of federal research grants disrupted about 1 in 30 NIH-funded clinical trials.

Benzinga

Moderna Q3 2025 Earnings Call Transcript

Moderna, Inc (NASDAQ:MRNA) reported third-quarter financial results on Thursday. The transcript from the company’s third-quarter earnings call has been provided below. MRNA is building positive momentum. Watch the momentum here This transcript is brought to you by Benzinga APIs. For real-time access to our entire catalog, please visithttps://www.benzinga.com/apis/for a consultation. Operator…

Euronews

First clinical trial testing pig kidney transplants in people launches in US

The small trial is the latest step in the quest for animal-to-human transplants.

The Independent UK

World’s first gene-edited pig kidney transplants begin in clinical trial

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