Perth have continued their NBL stranglehold over Adelaide, trailing at every break before winning 94-87.
The Wildcats silenced a record Adelaide Entertainment Centre crowd of 10,029 on Sunday with a fast finish, outscoring the 36ers 22-11 in the fourth quarter.
Kristian Doolittle paced a 14-2 Perth run which turned a 76-82 deficit into a 90-84 advantage.
Isaac White hit a corner three for Adelaide to trim Perth's lead to 90-87 with 44 seconds remaining, but missed another shot to tie the game from the same spot with 15 seconds left, before the Wildcats iced their seventh straight victory over Adelaide from the foul line.
Dylan Windler (18 points), Doolitte (16) and David Duke Jnr (16) led an even Perth charge.
"We just stayed with it for 40 minutes," Wildcats coach John Rillie said.
"Not always necessarily pretty, but we stayed with it.
"To see us close the game was pleasing."
Sixers superstar Bryce Cotton scored 23 against his old side, but at a wayward 8-of-24. White and Nick Rakocevic contributed 15 points each.
The 36ers led 18-17 at quarter-time before rebounding became a big problem for them.
After out-rebounding Adelaide 13-10 in the opening period, Perth smashed the home side on the boards 14-4 in the second, including 8-2 on the offensive glass, led by Windler.
Still, it was the 36ers - behind Rakovic playing his best quarter of the season and two last-second free throws from Matt Kenyon - who crept in front 45-44 at halftime.
The contest continued to seesaw after the break, the first three periods containing 35 lead changes, before Cotton gave the hosts a 76-72 cushion when he buried a triple - his fifth for the game - on the three-quarter time siren.
Cotton drained his sixth and seventh three-pointers early in the fourth as Adelaide's advantage moved to a game-high six points, before the 36ers went ice cold, missing 12 of their next 13 shots.
"I thought we played a really good, free-flowing third (quarter) and it got a little tight in the fourth," Sixers coach Mike Wells said.
"Give them credit for their defensive game plan which forced us into some tougher looks.
"We just didn't quite make the play there at the end."
