Two London clubs will battle it out in what will be billed as a six-pointer in the race for a Champions League place next season.
Both Arsenal and West Ham United are separated by just two points with the Irons sitting in fourth-place while the Gunners are in sixth.
Mikel Arteta will be expecting his side to show what they demonstrated in their 3-0 win against Southampton at the Emirates while David Moyes will be looking for improvement after his side were held to a goalless draw at Turf Moor.
A win for the Gunners could make for an interesting festive period as they look to make their claim as serious top four candidates while three points to West Ham will extend their lead to four points now that Manchester United's match against Brentford has been postponed.
What are the bookies saying ahead of the action?
Here are the latest odds from Grosvenor Sport:
- Arsenal 11/10
- Draw 13/5
- West Ham 49/20
18+ | UK only | Gamble responsibly | begambleaware.org | Odds subject to change
How to watch Arsenal vs West Ham on UK TV?
Arsenal's match against West Ham takes place on Wednesday, December 15 and kicks off at 8pm.
BT Sport 1's coverage starts at 7pm so you can catch all of the build-up ahead of the game.
If you're not a BT Sport subscriber, click here to upgrade or check out the latest packages.
Alternatively, BT Sport Monthly Passes are available for £25.
What is the early Arsenal vs West Ham team news?
The Gunners will consider Pierre-Emerick Aubameyang for selection after the Gabon striker was stripped of the captaincy due to a disciplinary breach.
Goalkeeper Bernd Leno and Sead Kolasinac remain unavailable.
For the visitors they could welcome back full-back Aaron Cresswell after missing the last four matches with a lower back injury.
