Manchester United lost Marcus Rashford to injury as they slipped to a demoralising 2-0 defeat at West Ham.
The England striker limped off early in the second half after Andriy Yarmolenko had given the hosts the lead, before Aaron Cresswell finished United off with a stunning free-kick. With Anthony Martial already missing through injury and youngster Mason Greenwood ill, United finished the match without a recognised striker and Jesse Lingard playing in attack.
Rashford's early departure will raise more questions about United's summer transfer business, when they failed to bring in a replacement for Romelu Lukaku.
Michail Antonio and Winston Reid also remain out with long term injuries.
Daniel James suffered a back injury against Leicester last week and Manchester United are hopeful he has overcome it and can play today.
Paul Pogba and Anthony Martial are both unlikely to be fit, while Luke Shaw and Eric Bailly remain sidelined by injuries.
"If we can keep a clean sheet it will be easier for our strikers, who will know we don't have to score twos, threes and fours all the time."
Team news
Manuel Pellegrini makes two changes to the West Ham side that drew 0-0 at Aston Villa las Monday.
Aaron Cresswell replaces the suspended Arthur Masuaku at left-back, while summer signing Pablo Fornals comes in for the injured Manuel Lanzini.
Nemanja Matic and Marcus Rashford are the only two players to remain from Manchester United's starting XI in the midweek Europa League game with Astana.
Mason Greenwood, United's match winner on Thursday, is not included in the squad, but Daniel James starts after recovering from a back problem.
Paul Pogba, Anthony Martial, Luke Shaw and Eric Bailly all remain sidelined by injuries.
"Manchester United played on Thursday night [in the Europa League] but they changed nine players so it will be a different team.
"We are in a good moment so, if we are playing against the big teams, we must show we can play in the same way."
Please allow a moment for updates to load
