Goals from Alexis Mac Allister and Leandro Trossard condemned West Ham to a 2-0 defeat at home to bogey side Brighton.
Mac Allister's first-half penalty and Trossard's breakaway goal maintained Brighton's unbeaten start to the season and made it three defeats from three matches for the Hammers.
West Ham have now played the Seagulls 11 times in the Premier League and not beaten them once.
Alarmingly, they have not yet scored a goal in the league this season, so it was surprising to see Gianluca Scamacca, the £30million summer signing who got off the mark against Viborg in Europe on Thursday, back among the substitutes.
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