A second-half defensive collapse saw Crystal Palace throw away the lead at Tottenham.
Eberech Eze's stunning free-kick looked to have been enough for Oliver Glanser to claim a second successive win in charge but late goals from Timo Werner, Cristian Romero and Heung min-Son saw Spurs complete a late comeback.
Substitute Brennan Johnson helped turn the match back in Spurs' favour, though, with a brilliant assist for Timo Werner's 77th-minute equaliser before Romero headed in a second soon after.
Captain Son Heung-min wrapped up the scoring two minutes from time after Johnson had sent him away to earn the hosts' a much-needed win in the battle for Champions League qualification.
Spurs had two weeks to prepare for this fixture but were up against a Palace side buoyed by the arrival of new boss Glasner, who won his first game in charge at home to Burnley last weekend.
It was the visitors who made the brighter start with Jordan Ayew blazing over before Jean-Philippe Mateta had a shot blocked by Emerson Royal.
Slowly Ange Postecoglou's side started to click with Son almost put through before he turned creator for what should have produced the opener.
Rodrigo Bentancur won back possession and Son sent Werner clear but he tried to round Sam Johnstone, who stood up well and thwarted the attacker in the 19th minute.
Play was back down the other end soon after when Jefferson Lerma's shot deflected into the path of Daniel Munoz but Guglielmo Vicario bravely dived in to deny the Palace wing-back.
Vicario made a superb save from Ayew with half an hour played only for the offside flag to be raised as the first rumblings of discontent occurred from the home crowd.
Spurs ended the first half with 82 per cent possession but had produced one shot on target against an organised Palace side in a 3-4-3 under their new boss.
Tottenham's tempo after the break was much-improved with Werner firing an effort across goal before he wanted a penalty with 53 minutes played.
Werner raced into the area and was caught by Daniel Munoz but referee John Brooks awarded a corner and VAR decided not to intervene.
The attacks kept coming with Son firing a first-time effort against the post from Dejan Kulusevski's pass before Eze was afforded a rare moment of space and won Palace a free-kick in a dangerous position.
Bentancur was booked for the cynical foul but worse was to follow for Spurs as Eze whipped the free-kick around the wall and beyond Vicario for a superb seventh goal of the campaign.
Postecoglou instantly turned to his bench with Johnson brought on and he side-footed a good chance over straight after his introduction.
Son was next to go close with a scuffed effort wide before Tottenham did find the breakthrough thanks to Johnson's tenacity.
Johnson first won back possession from Joachim Andersen and then got the better of Lerma before he teed up Werner at the back post to level in the 77th minute.
It was Werner's first goal in English football since April 2022 but Spurs very quickly made it 2-1.
James Maddison sent a floated cross into the area, which was headed home by Romero, before Son wrapped up the scoring with a fine finish into the bottom corner for his 13th goal of the season.
