Part of Piccadilly Gardens has been cordoned off by police after a man collapsed earlier this afternoon.
Police tried to resuscitate the 58-year-old at the scene.
He was taken to hospital by paramedics in a 'serious condition'.
Police confirmed the man's condition was life-threatening.
Coun Pat Karney, spokesman for the city centre, said: "Police were called to a collapsed 58-year-old.
"He was in a very bad condition. They tried to resuscitate him. He has been taken to hospital in a serious condition."
Photos from the scene show a cordon was put up around a bench. Tape was put up at the pedestrian area between Mosley Street and Piccadilly, earlier this afternoon.
An ambulance was parked at the scene.
Officers were pictured guarding the cordoned off area.
A spokesman for GMP said: "Police were called at around 1.35pm this afternoon (Thursday 23 July 2020) to reports of concern for the welfare of a man in Piccadilly Gardens, Manchester.
"The man’s condition is life-threatening and emergency services are treating him at the scene."
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