BRIT Award winner Dave dedicated his gong to his jailed older brother and people in prison during his acceptance speech for Best Album.
His album Psychodrama scooped a gong, and while he was up on stage he paid tribute to his brother, Christopher Omoregie.
Omoregie was jailed in 2010 for stabbing Sofyen Belamouadden to death during an attack at London's Victoria Station.
Then 18, he was put behind bars for 18 years.
"Thank you so much to everyone that's supported me my entire career," said Dave.
"My mum. My team. It's an honour to receive the award."
The Streatham-based rapper continued: "So many legends in this building today, you don't understand. So many legends.
"To Harry Styles, Stormzy, Lewis Capaldi, Billie Eilish.
"Everyone one I know thats inside doing their time, hold it down."
In his album, Dave raps about his brother in the song Drama, calling him "the only person I ever f***ing idolised” and “my hero”.
Dave blasted Boris Johnson during his rap performance at the ceremony, branding the prime minister a "real racist".
His lyrics were even more politically charged as he took poignant and clear swipes at everything from the state of Britain's politics to raising awareness of the Grenfell disaster and how residents still need a home.
Dave, whose full name is David Omoregie, took to a piano to perform his politically-charged song as powerful black and white images flashed across the top of the instrument.
"Our PM is a real racists," he tells the audience - who quickly applaud the statement.
In the show stopping performance, he then powerfully demands "Equality is a right."
During the thought-proving show, the Streatham-born rapper went as far as highlighting the attacks of of the new royal couple: "How the news treat Kate compared to how they treat Meghan."
The award-winning grime artist, who is also nominated for four BRIT Awards this evening, also led a powerful and tear-jerking tribute to the London Bridge attack victim Jack Merritt.
"We never had the same background, culture, colour or past - but you devoted your life to giving others a chance - and for that I'm so taken aback."
As Dave poured his heart into the powerful, message-filled rap, words such as "Black" and "Go Home" flashed up in the visuals during the stunning performance before leading a call for a more united country.
"Equal opportunities, people under scrutiny, no more immunity, way less hatred," he demands.
