Federal Newcastle MP Sharon Claydon has called on Prime Minister Scott Morrison to explain "how long he'd been sitting on this secret stash of Pfizer".
Ms Claydon said the Hunter Region had been "robbed of precious vaccines, leaving us all like sitting ducks, vulnerable and unprotected".
She said her disappointment at residents having their vaccines cancelled "turned to white-hot anger with the news that the Prime Minister has miraculously found 185,000 Pfizer vaccines to replenish our stocks".
"It's way too late to prevent Newcastle from going into another snap lockdown."
With Premier Gladys Berejiklian facing a backlash in the Hunter, Central Coast and other regions over the vaccine scandal, the Prime Minister came to her rescue with the extra doses - due over the next fortnight.
Federal Shortland MP Pat Conroy said Ms Berejiklian "waited too long to lock down the wealthy eastern suburbs of Sydney".
"Scott Morrison was an active accomplice, enthusiastically encouraging her to hold off," Mr Conroy said.
He said the Prime Minister was "on television urging Gladys Berejiklian to resist going into a full lockdown, as late as eight days into the Bondi outbreak".
"He now bears responsibility for what the Hunter and Central Coast are going through right now. The Prime Minister's complacency and 'it's not a race' attitude has resulted in our region being in lockdown and our health being endangered."
Asked about the Prime Minister's vaccine rescue, Swansea MP Yasmin Catley said: "So he should - that's his job".
"I want some clarification, though. I want to know when the Pfizer vaccinations are coming and when they will be rebooking the appointments they've cancelled."
Ms Catley, the Shadow Minister for the Hunter, had led calls for the Premier to overturn the decision to give 5500 Pfizer jabs from the Belmont Vaccination Hub to HSC students in Sydney's COVID hotspots.
The decision meant people with health conditions and those awaiting second shots had their Pfizer bookings cancelled.
She noted that Ms Berejiklian said "the buck stops with me" in her press conference on Thursday.
"As such, the community is seeking answers on when vaccine supply will be restored to the Belmont mass vaccination hub," she said.
She has written to the Premier, copying in NSW Health Minister Brad Hazzard and Hunter New England Health.
"Will NSW Health be contacting individuals who have had their appointments cancelled to arrange a new appointment date and time?" she said.
She said vaccination cancellations had caused "significant anxiety among the community who are desperate to get vaccinated, especially with the region now entering a snap lockdown".
Newcastle MP Tim Crakanthorp urged people to support each other, as the Hunter braces for a week of lockdown with five new cases of COVIDconfirmed in the region.
"For weeks we have been trying to avoid local cases and lockdowns, so it's very disappointing it's gotten to this," Mr Crakanthorp said.
"But now that we are here, it's important that we don't panic. First and foremost, we need to follow the stay-at-home rules and, if you're unsure, err on the side of caution."
Mr Crakanthorp was concerned that long lines at supermarkets had begun not long after the Premier announced the lockdown on Thursday morning.
"It is important to remember that these essential services will not close," he said.
"This may not be easy, but we will get through it. We need to be sensible and support each other."
Ms Catley's electorate traverses the Hunter and Central Coast, so she's well versed on life in lockdown.
The Central Coast, which has been in lockdown for about six weeks, recorded nine new COVID cases on Thursday. Eight were in one household, the other was linked to the Blacksmiths Beach gathering.
"While I understand people will be very frustrated by this lockdown, we have to understand it is unfortunate but necessary for us to come out the other side," Ms Catley said.
"If we want to make this lockdown as short as possible, stay home unless you absolutely have to go out."
