A man in his 30s was tragically killed in a major crash on the M57 in Prescot.
Emergency services were called to the scene, between junctions 3 and 4 shortly before 3pm on Monday.
It is believed that a Vauxhall Corsa had crashed among the traffic and road closures were quickly put in place.
Traffic was held as an air ambulance landed on the southbound carriageway to help paramedics, police and fire crews that were already at the scene.
But despite the work of officers and ambulance workers, the driver of the Corsa died at the scene.
The motorway remained closed overnight as an investigation took place.
Officers then had to arrange for recovery of the vehicle and carry out a clean up of the area.
In a statement, a spokesperson for Merseyside Police confirmed the man had died.
The force said: "We are appealing for witnesses following a fatal RTC this afternoon, Monday 7 December.
"At around 3pm, emergency services were called to the M57 in Prescot to reports of a collision involving a Vauxhall Corsa between junction 4 and junction 3.
Keep up to date with the latest news in your area by entering your postcode below
"The driver of the Corsa, a man in his 30s, was sadly pronounced deceased at the scene. He will be formally identified and his next of kin informed.
"The motorway will be closed for a considerable time and diversions are being put into place, so please avoid the area."
Enquiries are ongoing with the Roads Policing Unit to establish the circumstances.
Police urge anyone who witnessed this incident or was passing at the time and may have captured dashcam footage to contact them @MerPolCC or call (0151) 777 5747, with reference 589 of 7 December.
