Andy Robertson returns for Liverpool as Virgil van Dijk and Ibrahima Konate start at centre-back against Shrewsbury Town.
Rumours of a shock return for Lloris Karius are incorrect as Caoimhin Kelleher starts in goal with Conor Bradley making up the back five on the right side of defence.
In midfield, Fabinho starts alongside Tyler Morton and Elijah Dixon-Bonner as Jurgen Klopp opts for a mixture of experience and youth in his engine room.
Up top, Curtis Jones is named on the left side of the front three with Max Woltman leading the line for his full senior debut.
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Kaide Gordon will begin the game on the right of the attack with returning Reds boss Klopp naming a fairly strong bench that includes Roberto Firmino, Takumi Minamino and Joel Matip.
There's a place for versatile 17-year-old Isaac Mabaya among the substitutes as James Balagizi, Melkamu Frauendorf and James Norris are also selected.
But there is no place in the squad for Trent Alexnader-Arnold after the club confirmed the right-back registered a suspected positive COVID test shortly after the draw at Chelsea last weekend.
Liverpool team: Kelleher; Bradley, Konate, Van Dijk, Robertson; Fabinho, Morton, Dixon-Bonner; Gordon, Woltman, Jones. Subs: Adrian, Firmino, Minamino, Tsimikas, Matip, Mabaya, Norris, Balagizi, Frauendorf.
