Lionel Messi is among four PSG players who have tested positive for Covid-19, the club have confirmed.
French football has been on a break since before Christmas but is due to return on Sunday with the French Cup round of 32.
PSG had been due to play fourth-tier side Vannes on Monday night before next week's trip to Lyon in Ligue 1.
But they will be without Messi for four games, as he and teammates Juan Bernat, Sergio Rico, Nathan Bitumazala have tested positive for Covid.
Messi returned to Argentina during the winter break and tested positive upon his return to training.
The club will also be without Neymar for at least their next three games as the Brazilian continues his recovery from injury.
A PSG statement reads: "This Sunday 2 January's medical update concerns Leo Messi, Juan Bernat, Sergio Rico, Nathan Bitumazala and Neymar Jr.
"The 4 players that tested positive for Covid-19 are Leo Messi, .Juan Bernat, Sergio Rico, Nathan Bitumazala.
"They are currently in isolation and are subject to the appropriate health protocol.
"Neymar will continue his treatment in Brazil until 9 January with members of the Paris Saint-Germain medical and performance staff. His return to training is still expected to be in about 3 weeks."
PSG are due to play Real Madrid in the Champions League last 16 next month but with six weeks before that one, all four players could be back in contention.
