- A groundbreaking study suggests that a deficiency of naturally occurring lithium in the brain may be a key factor in the development of Alzheimer's disease.
- Researchers from Harvard Medical School found that lithium loss is one of the earliest changes leading to Alzheimer's, with reduced levels linked to impaired uptake and binding to amyloid plaques.
- The study demonstrated that a new compound, lithium orotate, can bypass amyloid plaques and successfully restore memory in mice.
- Unlike traditional lithium treatments, lithium orotate was effective at a significantly lower, non-toxic dose, mimicking natural brain lithium levels.
- These findings offer a revised understanding of Alzheimer's, suggesting new avenues for early diagnosis, prevention, and treatment, though human clinical trials are required for confirmation.
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