Furious Keir Starmer has blasted Liz Truss's war against the "anti-growth coalition" and said the mini-Budget was "as anti-growth as you could possibly be”.
The Labour leader said Ms Truss's "kamikaze" economic growth plan had pushed up mortgages, pointing to analysis by the party showing average buyers face £500-a-month hikes if interest rates hit 6%.
Financial research service Moneyfacts said the average two-year fixed-rate mortgage had breached 6% on Wednesday - the first time since 2008.
Mr Starmer was challenged on air for repeating the word "kamikaze" during a round of radio interviews but he retorted: "You understand how angry it makes me feel... to do something like that?
"People are going to have to pay the consequences."
Chancellor Kwasi Kwarteng summoned high street lenders and banks today following days of economic turmoil triggered by the disastrous mini-Budget.
The meeting was billed as part of regular talks but comes amid increasing woes in the lending market, with a number of banks pulling mortgage deals in the last week and hiking mortgage rates.
Lenders are understood to have asked Mr Kwarteng to consider extending the mortgage guarantee scheme, which protects lenders against losses when lending to first-time buyers.
The Prime Minister is under intense pressure over her economic plans after the tax-slashing mini-Budget spooked markets, causing vicious infighting at Tory conference in Birmingham.
In her keynote speech, Ms Truss attacked the "anti-growth coalition", which she said included "Labour, the Lib Dems, the SNP, the militant unions, the vested interests dressed up as think tanks, the talking heads, the Brexit deniers, Extinction Rebellion".
But Mr Starmer hit back, saying the PM herself was a "destroyer of growth".
Asked if he was an enemy of growth by BBC Radio Sheffield, he said: "For heaven's sake. The enemies of growth?
"She's just passed a kamikaze mini-budget which has lost control of the economy, is putting hundreds of pounds on people's mortgage bills, that is the absolute opposite of a plan for growth.
"She's... not just anti-growth, she's the destroyer of growth."
The Labour leader told BBC Surrey he hadn't paid off his own mortgage and warned that people will feel “frustrated that they’re now paying more - if they’re not on a fixed rate of course - they’re paying more as a direct result of the kamikaze politics of two weeks ago.
"That is just not fair, and I think they will be more than frustrated, if … not a little bit angry."
In another interview with BBC Radio Manchester he said: "The kamikaze mini-budget that Liz Truss put in place two weeks ago today has had a devastating impact on the economy.
"That kamikaze mini-budget is about as anti-growth as you could possibly be. It’s destroying growth.”
Tory party chairman Jake Berry admitted it was going to be a "difficult winter" but said people would see things start to turn around next year.
Asked when the country would know if the plan was working, he told LBC: "This is going to be a difficult winter.
"We have a war on the soil of Europe in the Ukraine, with a vile and illegal war.
"We have challenges around global supply chains still coming into our economy from Covid. We have global inflation.
"So this is going to be a difficult winter, but I hope and believe that people will start to see next year that our growth plan is turning the country around."
On a visit to Bilston, Wolverhampton, Mr Starmer said: "The Prime Minister has taken the economy, driven it into a wall, and (is) pretending that this is pro-growth.
"If you have consequences that increase mortgage payments by hundreds of pounds per month, that is anti-growth.
A Government spokesman said there are a "range of factors" affecting mortgage interest rates.
They also said the Government is doing "what it can" to support people with the rising costs of energy through the price guarantee and other measures, and that the growth plan and changes to taxes are putting money "back in the pockets" of working people.
