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Tullamarine homicide investigation continues after Katie Perinovic and three children found dead in Melbourne home

Katie Perinovic was remembered as a well-liked neighbour with happy children.(Facebook)

Police are continuing their search for answers after the deaths of a woman and her three children at a home in Melbourne's north-west

The bodies of Katie Perinovic, her three-year-old son Matthew and two daughters Claire and Anna, aged seven and five, were found in their Tullamarine home on Thursday.

Tomislav Perinovic, 48, husband of Ms Perinovic and the children's father, called emergency services to report the deaths.

Police said he was assisting police with their enquiries on Thursday, but stressed with an ongoing investigation it was important not to speculate about what happened.

No-one has been charged over the deaths and homicide detectives do not believe anyone else is involved.

The Homicide Squad is leading the investigation.(ABC News: Patrick Rocca)

Asked if murder-suicide was a possibility, Acting Deputy Commissioner Bob Hill said: "There is a number of possibilities, and that's one that could possibly be relevant to this particular event".

A large police presence remained at the Burgess Street home into Thursday night as homicide detectives, forensic investigators and uniformed officers investigated the scene and interviewed neighbours.

Tributes have been left at the family's home as the community mourns.(ABC News: Beth Gibson)

Police declined to comment further on the investigation this morning.

A small number of detectives and uniformed police were at the home during the morning and the house was cordoned off behind police tape.

'Smiley face Katie' was loved by the neighbourhood, friend says

Neighbours remembered Ms Perinovic as someone who always made the time to stop and chat.(Facebook)

Ms Perinovic, a physiotherapist, was described by neighbours as "the best mum" and "one of the nicest people you'd meet".

Another neighbour remembered the children as "gorgeous, very friendly and happy".

Neighbour and friend Marie Groves said a day later "it still hasn't really sunk in properly".

"It hasn't sunk in that I'm not going to walk out the door and see her walking past to the milk bar and picking up pizzas with the kids," she said.

"I'm not going to be able to be at the park and see Matthew jumping on the trampolines."

Ms Groves said her children were friends with Matthew, Claire and Anna, and Ms Perinovic was "such a feature of the neighbourhood".

"She was Katie, smiley face Katie, who would always stop and chat," she said.

A friend of Katie Perinovic says the neighbourhood is still shocked by the news.

She said the Tullamarine neighbourhood was still struggling to come to terms with the news.

"It's incomprehensible, we just cannot understand how this could have happened to Katie."

She said Ms Perinovic was proud of her physiotherapy work, which she returned to part-time when Matthew was old enough.

It was during the days when Ms Perinovic was home with the three children that she and Ms Groves bonded, she said, taking their kids to the park and watching them play together.

Katie and Tomislav Perinovic pictured together in 2019.(Facebook)
Gloved and masked investigators returned to the home late on Friday morning.(ABC News: Beth Gibson)

Acting Assistant Commissioner Mark Galliott said on Thursday the sudden loss of life, including three children, was difficult to comprehend.

"This will have long-lasting effects on the police that attended, on extended family, the community, the neighbourhood, the emergency services and everybody else involved," he said.

"They'll be lifelong memories that they'll have to deal with and so we'll make sure that the welfare of our members and the emergency services that attended are paramount."

Police urged anyone with information that may help with their investigation to contact Crime Stoppers.

Police remained at the crime scene on Friday morning as the investigation continued.(ABC News: Patrick Rocca)
Forensic officers were called to the scene on Thursday afternoon.(AAP: James Ross)
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