Gina Rinehart's Hancock Iron Ore is cutting jobs as part of a plan to keep its massive Roy Hill mine in Western Australia operating for another decade.
It did not say how many jobs would be lost, but a spokesman told AAP the figure of 300 to 500 being floated in some media outlets was inaccurate.
The West Australian on Wednesday suggested that more than 150 roles would go.
The mine has a workforce of around 2,800 employees, making it one of the largest in Australia.
The move came after Hancock Iron Ore completed an annual operational review to identify how ore is mined, processed and blended across its operations.
"We continuously look at optimising our mine plan and the latest iteration extends our life of mine by 10 years, maximising how much of the orebody we can turn into product and reduce the amount of waste we mine," a spokesman said.