It's clear there's not a lot of love lost between them, despite promises of wanting to work closely together and pleas for a kinder politics.
In recent months Wales' First Minister has said Boris Johnson's attempts to fix the fuel crisis were "exploitative, arrogant, derisory". He has said the Prime Minister has a "confrontational approach". He has criticised the way he made announcements about covid rules in England without mentioning that they were different in Wales and condemned Mr Johnson's comments on Margaret Thatcher having given the UK a "big early start" in the fight against climate change when she closed coal mines as "crass and offensive".
At Labour's party conference, Mark Drakeford got a standing ovation for telling delegates the UK Government is "incompetent to its core"
And most recently, Mr Drakeford said that the Prime Minister was "the very bottom of the barrel".
But when he was asked earlier in October, Mr Johnson said of the First Minister: "I love the guy," telling him to pick up the phone to ring him more.
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On Thursday, Welsh secretary Simon Hart, a Conservative MP who represents Carmarthen West and South Pembrokeshire, and his deputy David TC Davies, Conservative MP for Monmouth, appeared at the Welsh Affairs Select Committee.
In response to the First Minister's latest comments, Mr Davies told the committee: "[What] the Secretary of State has always sought to do is to build a good relationship with the First Minister and his ministers.
"He has a different political view but we rise above that and we want to work with the Welsh Labour Government. And so, you know, we wouldn't want to respond to insults, they're not helpful and if that's how the First Minister wants to conduct himself that's up to him.
"That's not how we conduct ourselves here. We want a good, professional, mature relationship with the Welsh Labour Government."
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