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The Independent UK
The Independent UK
National
Rebecca Whittaker

Woman’s ‘remarkable’ recovery after cell therapy resets her immune system

  • A 47-year-old woman suffering from three severe, life-threatening autoimmune diseases for over a decade has achieved a "remarkable" recovery following CAR-T cell therapy.
  • The patient, who previously required daily blood transfusions and tried nine different treatments without lasting success, received the cell therapy at University Hospital Erlangen in Germany.
  • Within weeks of the treatment, her autoimmune conditions responded, leading to over a year of treatment-free remission and significantly improved quality of life.
  • CAR-T cell therapy involves engineering a patient's own T-cells to target and destroy harmful B-cells, which are implicated in autoimmune diseases, similar to its use in treating certain cancers.
  • Researchers believe that using CAR-T therapy earlier for patients with severe autoimmune disease could prevent complications from prolonged ineffective treatments and improve patient outcomes.

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