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The Independent UK
The Independent UK
National
Julia Musto

Why women are at higher risk of having Alzheimer’s than men

  • Women are twice as likely as men to develop Alzheimer's disease, accounting for almost two-thirds of American sufferers.
  • Scientists are investigating two primary biological differences: chromosomal variations, particularly genes on the X chromosome.
  • The natural decline of reproductive hormones during menopause is also considered a significant factor contributing to women's increased risk.
  • Research suggests that women who received hormone replacement therapy after age 70 exhibited higher levels of the Alzheimer's hallmark protein “tau” and greater cognitive decline.
  • Further studies are required to fully comprehend the complex associations between menopause, hormonal changes, and the long-term risk of developing Alzheimer's.

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