James Rodriguez felt 'fatigued' after the game with Sheffield United and so has not been risked for this evening’s game with Wolves.
Rodriguez started the game at Goodison on Sunday but was replaced after 78 minutes by Bernard.
The game was Rodriguez’s first back in the team having missed the previous three matches because of injury.
Rodriguez has now missed 13 Premier League games this season and the expectant 6,500 Evertonians inside the ground tonight will have to wait until next term to see the Colombian in the flesh.
Carlo Ancelotti said: "James is out because he was a little bit tired.
"He didn’t play, he was out, then he played against Sheffield, we prefer not to take a risk."
Everton will hope that Rodriguez has recovered in time for Sunday’s trip to Manchester City, the final game of the season.
The 29-year-old has made 22 appearances in the Premier League, scoring six goals and registering two assists.
Everton team to face Wolves : Pickford; Mina, Keane, Godfrey; Coleman, Allan, Doucoure, Digne; Richarlison, Calvert-Lewin, Sigurdsson
Substitutes: Olsen, Holgate, Delph, King, Iwobi, Nkounkou, Bernard, Gomes, Davies
