Hugo Lloris is not playing for Tottenham against Manchester City today because he is nursing a muscle injury.
Paulo Gazzaniga is starting in his place behind a back three of Jan Vertonghen, Davinson Sanchez and Toby Alderweireld.
Speaking to Sky Sports ahead of kick-off, Mauricio Pochettino said: "Hugo has a small muscle problem. Hopefully it’s not a big issue and he can be ready for Tuesday (Brighton at home). It would be a risk for him to play today and that’s why we decided to leave him in London.
"It's a massive boost for Gazzaniga to play."
Pochettino has made a total of five changes to the team that started on Wednesday night, with Davinson Sanchez, Juan Foyth, Ben Davies and Eric Dier also coming in.
Man City team to face Spurs
Starting XI: Ederson; Waler, Stones, Laporte, Zinchenko; Gundogan, De Bruyne, Foden; Bernardo, Aguero, Sterling
Subs: Muric, Jesus, Mahrez, Otamendi, Fernandinho, Sane, Silva
Spurs team to face Man City
Starting XI: Gazzaniga; Alderweireld, Sanchez, Vertonghen; Foyth, Alli, Dier, Davies; Eriksen, Son, Lucas
Subs: Vorm, Rose, Skipp, Llorente, Jansen, Wanyama, Walker-Peters
