A man arrested after a hit-and-run on Deansgate has been released under investigation.
The victim, a man in his 20s, was hit by a Toyota Prius at around 4.40am on Tuesday.
It is understood the car did not stop following the collision.
Police said the man was left with 'potentially life-changing injuries'.
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A man was arrested on suspicion of causing serious injury by dangerous driving; dangerous driving; and failing to stop after a collision.
Greater Manchester Police said the man has since been released under investigation.
A large section of Deansgate was sealed off in both directions on Tuesday.
In a statement following the incident, GMP said in a statement: "At around 4.40am this morning (August 27) police were called to reports of a collision between a Toyota Prius and a pedestrian on Deansgate, in Manchester City Centre.
"The driver left the scene following the collision.
"The pedestrian - a man who is believed to be in his 20s - has been taken to hospital with potentially life changing injuries."
