Man City return to action tonight as they take on Arsenal at the Etihad Stadium.
The top-flight campaign has been postponed for more than three months due to the coronavirus pandemic.
But the action resumes on Wednesday, with Aston Villa hosting Sheffield United at Villa Park at 6pm.
And in the second fixture after the restart, reigning champions Man City take on Arsenal behind-closed-doors in the North West of England.
The fixture at the Etihad Stadium gets underway at 8:15pm on Wednesday, June 17.
It will be shown live exclusively by Sky Sports. Coverage on their Premier League and Main Event channels begins at 8pm, 15 minutes before kick-off.
Main Event is channel 401 on Sky while Premier League is channel 402.
Man City are currently second in the table, 25 points adrift of leaders Liverpool.
It means Jurgen Klopp's side can win the title on Sunday with victory over Merseyside rivals Everton should Arsenal triumph against Man City tonight.
“We are going to play and we will adapt as quickly as possible,” said Pep Guardiola.
“They [the players] came back really well. We have absolutely no complaints. But the way we are right now, like other clubs, we don’t know.
“Tomorrow we will see the level of the team and from there we will see what we can do better. All the teams in the Premier League have just three and a half weeks.
“We know it isn’t enough, but it is what it is. Everyone suffered this situation, personally and economically, and we have to adapt.
“They are training well, but I don’t know exactly their condition.”
As for the Gunners, they are ninth in the standings, eight points adrift of Chelsea who occupy the fourth and final Champions League spot.
"Obviously, we had a big turning point with the coronavirus and being away from each other for three months, but we've been trying to keep going in our direction, being close in contact and communication with our players and our staff and I think we are in a really good position to move forward," said Arsenal head coach Mikel Arteta.
"We have some uncertainties that we cannot control and we do not know how the players are going to respond now, playing every three days after three months, but most of the clubs are in the same position.
"We will try to adapt and to make the most out of it. We don't try to find any excuses. We'll go for it and enjoy it because I think we're all missing football so much that we're all desperate to get back playing."
