Leo Varadkar will sit down with Ryan Tubridy live on The Late Late Show on Friday night.
The Taoiseach will discuss the latest restrictions and his coronavirus "road map" which he will have revealed a few hours earlier.
Mr Varadkar is also likely to talk about the effort of the public so far and his messages for the future of our lives and the economy.
Running order
RTE has confirmed that the Taoiseach will be one of the first guests on the show, with it kicking off at 9.35pm.
It's not clear if he will be very first on but is likely to be one of the first two.
This will mean a quick turnaround for the Taoiseach who is expected to brief the nation at 6:30pm.
How to watch it
The show will be live on RTE One and you can also tune in on the RTE Player, or watch it back on the Player over the next few days.
The Irish Mirror will also have updates on what The Taoiseach says throughout the night via our dedicated live blog.
