Taoiseach Micheal Martin is set to announce the latest lockdown exit plan in a nationwide address today.
Mr Martin is expected to reveal which restrictions will be eased in a State of the Nation address around 6pm.
NPHET have issued recommendations to the Government regarding the pandemic situation in Ireland.
Additionally, a special sitting of the Cabinet met last night to discuss the advice given by NPHET.
Here are the changes the Taoiseach is expected to discuss during his address:
Full reopening of construction activity
Return of inter-county travel
Reopening of hairdressers, barbers, and salons
Three households can meet in a back garden
Vaccinated households can meet with another household indoors
Phased return of non-essential retail commencing with click and collect and outdoor retail, for example garden centres/nurseries
Recommencement of personal services on a staggered basis
Reopening of museums, galleries, and libraries
Recommencement of religious services on a staggered basis
Health Minister Stephen Donnelly has hinted that "nice things" will come from last night's Cabinet meeting in a positive update regarding concerns around isolation during lockdown.
The Fianna Fail TD said he had come from a "very constructive, very positive" talk with Chief Medical Officer Tony Holohan and Deputy CMO Ronan Glynn after this evening's NPHET briefing and said Ireland was in "a good place".
Speaking on the way into Government Buildings tonight, Mr Donnelly said: "I've had a very constructive, very positive conversation with the CMO and the Deputy CMO post-NPHET (briefing) really about what's possible based on where we are, and the good news is we're in a good place.
"People have stuck with the public health advice - by European standards, we're doing well and we've been doing well for some time.
"What it means is that this evening we can have a positive conversation. I'm very concerned about people's mental health, very concerned about the isolation that people have had to deal with for a very long time.
"Certainly, the kinds of measures that we're going to be talking about tonight will address those things.
"I think ultimately huge credit goes to the nation, to the Irish people, for sticking with this, for putting Ireland in a good position so that we can have the kind of conversation we need to have now while some other countries around the world, including in Europe, are having much more difficult conversations."
