The Republic of Ireland have a great chance of taking a huge step towards qualification for next year's UEFA European Under-21 Championship this afternoon.
Jim Crawford's side currently top their qualifying group by three points, but Italy are in second place and have a game in hand after their clash with Iceland was postponed last week.
The hosts are set to field their U20's side for today's game after seven of their U21's squad tested positive for Covid-19.
Crawford has also lost some players from his squad in recent days, with defender Dara O'Shea and midfielder Jason Knight both joining Stephen Kenny's side due to Covid-19 ruling a number of senior players out of Wednesday's match with Finland.
Here's everything you need to know about Italy v Ireland:
Where and when is it?
The match takes place at the Arena Garibaldi in Pisa on Tuesday, October 13.
What time is kick-off?
The action is due to get underway at 4pm Irish time.
What channel is it on?
The game is not being televised live in Ireland, but will be shown by Italian station RAI 2, who may also stream it on their website.
You can follow all the action with The Irish Mirror's live blog.
Republic of Ireland U21 squad
Goalkeepers: Gavin Bazunu (Rochdale, on loan from Manchester City), Ed McGinty (Sligo Rovers)
Defenders: Nathan Collins (Stoke City), Darragh Leahy (Dundalk), Conor Masterson (Queens Park Rangers), Conor McCarthy (St. Mirren), Danny McNamara (St Johnstone, on loan from Millwall), Lee O’Connor (Tranmere Rovers, on loan from Celtic), Thomas O’Connor (Southampton), Liam Scales (Shamrock Rovers)
Midfielders: Conor Coventry (West Ham United), Will Ferry (Southampton), Daniel Mandroiu (Bohemians), Connor Ronan (Grasshopper Zurich, on loan from Wolverhampton Wanderers), Will Smallbone (Southampton), Jack Taylor (Peterborough United), Danny Grant (Bohemians)
Forwards: Jonathan Afolabi (Dundee, on loan from Celtic), Zach Elbouzedi (Lincoln City), Joshua Kayode (Carlisle United, on loan from Rotherham United), Michael Obafemi (Southampton)
Quotes corner
Republic of Ireland Manager Jim Crawford: "We are looking forward to the game. We know just how important this game in terms of the Group but also in terms of our chances of qualifying for the finals tournament.
"We have kept an eye on what has been going on and we will be as prepared as we can be for the game. Our staff have been working hard to provide us with as much information as possible as we can get on the Italian team.
"Everyone with us is fit and available. Including the staff, we had 34 tests done and 34 came back negative, so there is a lot of credit to the players for following the protocols.
"This game is a great opportunity for us and we have been working hard in training all week. We have some really good players and we want to continue on the good form that we have showed already in this qualifying campaign."
Betting odds
Italy win: 5/6
Ireland win: 14/5
Draw: 5/2
