It's another step on the way to clinching the title for Steven Gerrard's league leaders.
Rangers are on course for their first Premiership title in 10 years and they make the short trip to Lanarkshire looking to move three points closer.
Hamilton are the hosts and Brian Rice's side could do with an upset to kickstart another survival push.
They've slipped to the bottom of the table but have games in hand over the likes of Ross County and Kilmarnock.
Rangers have a 23 point lead over rivals Celtic and, at this stage, it's simply about getting over the line by any means necessary.
It's sure to be an eventful game so here's everything you need to know about the fixture.
When and where will the game take place?
The match will take place at the Fountain of Youth Stadium on Sunday February 7.
Kick-off is at 12pm.
What channel is it on?
The game is live on Sky Sports Football.
Coverage begins at 11am.
Will there be a live stream?
Yes. Now TV subscribers will be able to stream the action.
Where else can I follow the action?
You can follow it right here on dailyrecord.co.uk of course! We'll be running a live blog throughout the evening, bringing you all the key moments as well as post-match reaction and analysis.
Talking points, player ratings, manager reaction and a whole lot more will also be available on our website following the final whistle.