Motorists are being asked to avoid the Westlink as police deal with an incident.
Details have not been revealed yet, but it is understood officers are dealing with an ongoing incident on the Westlink in the M2 direction.
Drivers should seek an alternative route.
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A PSNI spokesperson said: "Police are dealing with an incident on the Westlink in the M2 direction at present. Motorists should avoid the area and seek an alternative route."
At 6.45pm on Wednesday, police said the Westlink had re-opened, however it would take some time for the traffic build up to clear.
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