UPDATED: September 9, 2021

We have finally arrived at Week 1 of the 2021 NFL season! Let's set those Week 1 lineups with a little help from my weekly PPR fantasy football rankings.

Wise decisions go a long way and while you can't lose a league in Week 1, you can overthink easy decisions. Remember to always churn those last couple bench spots to make sure you're bringing your best options to your lineup. Every lineup spot counts!

Week 1 Start 'Em, Sit 'Em: QUARTERBACKS | RUNNING BACKS | WIDE RECEIVERS | TIGHT ENDS | KICKERS | TEAM DEFENSES

MORE: Week 1 Rankings & Articles Hub

Week 1 Rankings (PPR)

• QUARTERBACKS
• RUNNING BACKS
• WIDE RECEIVERS
• TIGHT ENDS
• FLEX
• KICKERS
• TEAM DEFENSES (DST)

RUNNING BACKS

1. Christian McCaffrey, CAR (vs. NYJ)
2. Dalvin Cook, MIN (at CIN)
3. Alvin Kamara, NO (vs. GB)*
4. Derrick Henry, TEN (vs. ARI)
5. Aaron Jones, GB (at NO)*
6. James Robinson, JAC (at HOU)
7. Jonathan Taylor, IND (vs. SEA)
8. Austin Ekeler, LAC (at WAS)
9. Joe Mixon, CIN (vs. MIN)
10. Najee Harris, PIT (at BUF)
11. Ezekiel Elliott, DAL (at TB)
12. Nick Chubb, CLE (at KC)
13. Saquon Barkley, NYG (vs. DEN)
14. Antonio Gibson, WAS (vs. LAC)
15. Clyde Edwards-Helaire, KC (vs. CLE)
16. Chris Carson, SEA (at IND)
17. David Montgomery, CHI (at LAR)
18. Raheem Mostert, SF (at DET)
19. Mike Davis, ATL (vs. PHI)
20. D'Andre Swift, DET (vs. SF)
21. Miles Sanders, PHI (at ATL)
22. Myles Gaskin, MIA (at NE)
23. Ty'Son Williams, BAL (at LV)
24. Darrell Henderson, LAR (vs. CHI)
25. Kareem Hunt, CLE (at KC)
26. Chase Edmonds, ARI (at TEN)
27. Damien Harris, NE (vs. MIA)
28. Josh Jacobs, LV (vs. BAL)
29. Javonte Williams, DEN (at NYG)
30. Nyheim Hines, IND (vs. SEA)
31. Ronald Jones, TB (vs. DAL)
32. Trey Sermon, SF (at DET)
33. Melvin Gordon, DEN (at NYG)
34. Jamaal Williams, DET (vs. SF)
35. James White, NE (vs. MIA)
36. Leonard Fournette, TB (vs. DAL)
37. Tevin Coleman, NYJ (at CAR)
38. A.J. Dillon, GB (at NO)*
39. David Johnson, HOU (vs. JAC)
40. Devin Singletary, BUF (vs. PIT)
41. James Conner, ARI (at TEN)
42. Zack Moss, BUF (vs. PIT)
43. Michael Carter, NYJ (at CAR)
44. Sony Michel, LAR (vs. CHI)
45. Kenyan Drake, LV (vs. BAL)
46. Giovani Bernard, TB (vs. DAL)
47. Mark Ingram, HOU (vs. JAC)
48. Tony Pollard, DAL (at TB)
49. J.D. McKissic, WAS (vs. LAC)
50. Alexander Mattison, MIN (at CIN)
51. Tony Jones, NO (vs. GB)*
52. Rhamondre Stevenson, NE (vs. MIA)
53. Damien Williams, CHI (at LAR)
54. Rashaad Penny, SEA (at IND)
55. Ty Johnson, NYJ (at CAR)
56. Joshua Kelley, LAC (at WAS)
57. Phillip Lindsay, HOU (vs. JAC)
58. Joshua Kelley, LAC (at WAS)
59. Devontae Booker, NYG (vs. DEN)
60. Trenton Cannon, BAL (at LV)

* - game is being played in Jacksonville