Video shows flames engulfing a derelict building in the east end which has left smoke billowing across Glasgow's sky.
Fire crews have raced to the scene of the massive blaze near Duke Street.
East end residents earlier reported hearing a huge explosion, while several have posted pictures of smoke billowing into the sky across Glasgow.
Video shows a building on fire at the old scrapyard near Todd Street, close to the former Joanna Dee's nightclub.
Meanwhile pictures show police have closed off the roads in the surrounding area.
A Scottish Fire and Rescue spokesperson confirmed to Glasgow Live: "We're in the vicinity of Duke Street in Glasgow we're attending a derelict building on fire.
"We got quite a lot of repeat calls in around 8.40pm."
Glasgow Live have also contacted Police Scotland for comment.
