Gareth Anscombe handed Wales their first World Cup injury scare of the summer when he limped from the Twickenham pitch during Sunday's warn-up clash against England.
The Wales fly-half, a key figure in the record 14-match winning streak, picked up a knee injury midway through the first half and was replaced by Dan Biggar.
Aided by two Wales medics, Anscombe left the field in clear discomfort after 33 minutes.
He had sustained the injury earlier in the match, but tried to play on.
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But after limping around for a while in the hope of running off the problem, Anscombe finally had to succumb.
Despite sustaining the injury, Anscombe was still able to make one scintillating individual break.
But he had also looked in clear pain when attempting a clearance kick and the writing appeared to be on the wall.
Anscombe, dressed back in his tracksuit, was seen on the Wales bench in the second half with crutches.
Wales boss Warren Gatland will be desperately hoping it is not bad news for his number one fly-half and Anscombe quickly recovers.
There have been suggestions Gatland only plans to take two 10s to the World Cup in Japan, with Rhys Patchell the third cab on the rank waiting to be called up.
The England game at Twickenham is the first of four World Cup warm-up matches for Gatland's side. They meet England again in Cardiff next weekend, followed by back-to-back games with Ireland.
