Four branches of Vue Cinemas in Wales will shut for three days a week to save costs following the delayed release of James Bond film No Time To Die.
In total nearly a quarter of Vue cinemas will reduce their opening hours and remain shut on Tuesdays, Wednesdays and Thursdays.
The changes will affect Vue Cardiff, Vue Carmarthen, Vue Rhyl and Vue Swansea as well as 17 other of the chain's 91 sites.
The news comes after cinema chain Cineworld announced it would temporarily close 127 Cineworld and Picturehouse sites in the UK.
Odeon has also taken the decision to close a quarter of its 120 cinemas from Monday to Thursday.
Get stories like this straight to your inbox with our newsletters.
The chief executive of Vue Cinemas previously said cinema chains were dealt a "body blow" by the delay to the next James Bond film, No Time To Die, until April next year.
Marvel film Black Widow, sci-fi blockbuster Dune and Jurassic World: Dominion have also delayed their release dates as a result of the global pandemic.
Tim Richards said on Monday: "Our problem right now is we have no movies. This was a big blow for us. We're likely going to make it through; I'm concerned about the independents and the small regional operators right now that are going to really struggle, and when they close they may not reopen."
Things to do where you live:
Five of the branches with reduced opening hours are in London, including the chain's large cinema in Leicester Square.
The affected Vue sites are: Vue Accrington, Vue Altrincham, Vue Barrow, Vue Birkenhead, Vue Blackburn, Vue Cardiff, Vue Carmarthen, Vue Cleveleys, Vue Dagenham, Vue Hull Princes Quay, Vue Lancaster, Vue Newbury, Vue Piccadilly, Vue Redditch, Vue Rhyl, Vue Scunthorpe, Vue Shepherds Bush, Vue Stroud, Vue Swansea, Vue West End (Leicester Square) and Vue Wood Green.
