Arsenal begin a new era of sorts this afternoon against Vitoria after Granit Xhaka was stripped of the captaincy.
The midfielder paid the biggest price for twice telling fans to "f*** off" in a recent home game, ending his time with the armband after just over a month.
The Gunners needed Nicolas Pepe to save them in the reverse fixture two weeks ago, the club-record signing scoring two late free kicks against the European minnows.
Arsenal are making a surprise return to Wednesday's European football schedule after a number of seasons on a Thursday after kick-off was brought forward by a day to accommodate Vitoria's rivals Braga.
TV channel and live stream information
The match will be televised live on BT Sport 2, and can be streamed live online via the BT app and website.
Kick-off is at 3.50pm GMT.
You can follow all the action and analysis on Standard Sport's LIVE blog with Simon Collings in Portugal.
Prediction: Vitoria 1-2 Arsenal
The close shave in the reverse fixture is still fresh in the memory and Vitoria will do well to score early again today.
Superior fitness levels should see the Gunners through, though there is no accounting for their defensive frailties.