Arsenal head to Portugal for an early kick-off against Vitoria de Guimaraes on Wednesday as the Gunners look to consolidate top spot in Europa League Group F.
Unai Emery's side have won all three group-stage games so far this season, but needed two late Nicolas Pepe free-kicks to avoid a shock upset vs Vitoria SC at the Emirates on matchday three.
That 3-2 victory sees the Gunners sitting top of the group by three points, with a six-point gap between themselves and third-placed Standard Liege.
Another win would all but guarantee their place in the knockout stages, but Vitoria's lively display in north London will serve as a warning that Emery's side cannot take anything for granted.
Europa League preview
Vitoria SC vs Arsenal
Venue: Estádio D. Afonso Henriques
Kick-off time: 3:50pm GMT, Wednesday November 6
Arsenal team news and injuries
Emery must decide whether to recall Granit Xhaka to his squad, with the away trip to Portugal perhaps an ideal time to bring the captain back in following his fallout with Arsenal fans.
Reiss Nelson is the other other absentee for Arsenal, with Emery once again likely to opt for a rotated lineup as he has done in the cups this term.
Arsenal predicted lineup: Martinez; Bellerin, Mustafi, Holding, Kolasinac; Torreira, Willock; Maitland-Niles, Saka, Pepe; Martinelli
Why is Vitoria vs Arsenal kicking off so early on Wednesday?
Vitoria play their games at the Estadio D. Afonso Henriques, which is within 25 minutes drive of rivals Braga who are also competing in the Europa League this season.
Braga host Besiktas at the Braga Municipal Stadium on Thursday at 8pm GMT.
To prevent both sets of fans ascending on the area on the same day, Vitoria's home game with Arsenal has been brought forward.
The early kick off time is to accomodate Champions League broadcasters with Bayern and Juventus in action against Olympiacos and Lokomotiv Moscow, respectively, from 5.55pm GMT.
Head to Head record (H2H)
This will be the second time the two sides have met in an official Uefa competition after the Gunners won 3-2 in north London on matchday 3.
Tickets
Arsenal tickets are still available to buy - click here for more information.
Betting tips and odds
- Vitoria to win: 23/10
- Draw: 27/10
- Arsenal to win: 23/20
Correct score
| Scoreline | Vitoria win | Arsenal win | Draw |
| 1-0 | 12/1 | 9/1 | 0-0 (13/1) |
| 2-0 | 14/1 | 11/1 | 1-1 (6/1) |
| 2-1 | 10/1 | 15/2 | 2-2 (10/1) |
| 3-0 | 30/1 | 17/1 |
Odds provided by Betfair. Click here to place a bet. Odds correct as of November 4.
Prediction: Vitoria 1-2 Arsenal
The Gunners' close shave in the reverse fixture is still fresh in the memory, and Vitoria will look to hit the visitors early.
Arsenal should still see out a win in the second half with greater fitness, but it could be another tight affair.
Live stream details and TV channel information
The match will be televised live on BT Sport 2, and can be streamed live online via the BT app and website.
You can follow all the action and analysis on Standard Sport's LIVE blog, with expert analysis from Simon Collings.
