Vicky Phelan has said that she is moving to a new trial after her doctors weren't "seeing the results that they would like" from her treatment in the US.
The mum-of-two broke her social media silence on Thursday morning to update on the "bad news" she had received and tell followers that she was now back Stateside.
The Kilkenny woman returned to the States on Sunday and has been meeting with her doctors since.
Growth in two of her tumours means that she now has to explore new treatment methods.
She said in a Facebook post: "I am back in the States since Sunday evening and met with my doctor yesterday (Tuesday) to discuss a plan going forward...
"Basically, my team are not seeing the results that they would like and think it would be best if I come off my current trial and start on a new (but similar) trial which has just started enrolling patients on it this week.
"And so, following a LOT of thinking over the past month I decided after yesterday's meeting and results from my last scan which showed growth in two of my tumours, that I would move to this new clinical trial and give it a shot.
"I need to have a series of scans and tests done next week before I start on this new treatment regime but it will be very similar to the clinical trial I was on with treatment scheduled every two weeks and three drugs being administered.
"I will post a video update next week once I know more and once I have settled back in over here. I am very emotional at the moment. I did not want to come back!!! I spent the first two days this week crying every time I thought of my kids and I found it so difficult trying to hold it together when I spoke to them on FaceTime.
"I almost booked a flight home!!! I am feeling less homesick and less teary today. It was so much harder coming back this time than when I came over in January. I will just take it one day at a time at the moment so please bear with me.

"Thank you all for your wonderful support, as always."
The brave woman had not been heard on social media for a period and explained that she wanted to "get her head around some bad news" and spend as much time as possible with her family.