A dramatic Day 7 at Flushing Meadows saw Novak Djokovic was thrown out of the tournament after he hit a line judge with the ball.
The top seed swatted away a ball in a fit of frustration and hit a lineswoman in the throat. Lengthy discussions ended with the Serbian defaulted.
Earlier in the day, 2016 women's champion Angelique Kerber was dumped out by American Jennifer Brady.
But 2018 winner Osaka restored order in the final match at Arthur Ashe Stadium with an impressive display of power and patience against the giant-killing Estonian Anett Kontaveit.
Follow all the action with Standard Sport's LIVE blog.
- Djokovic defaulted after ball strikes lineswoman
- Osaka powers past Kontaveit
- Zverev eases past Davidovich Fokina
- Putintseva makes history by Martic
- Brady brushes aside Kerber
- Britain's Salisbury into semi-finals
Order of Play (times in BST)
Arthur Ashe Stadium
5pm: (23) Yulia Putintseva (Kaz) 6-3, 2-6, 6-4 (8) Petra Martic (Cro), (1) Novak Djokovic (Ser) v Pablo Carreno-Busta (Spa)
12am: (12) Denis Shapovalov (Can) v (7) David Goffin (Bel), (4) Naomi Osaka (Jpn) v (14) Anett Kontaveit (Est)
Louis Armstrong Stadium
4pm: (28) Jennifer Brady (USA) 6-1, 6-3 (17) Angelique Kerber (Ger), Alejandro Davidovich Fokina (Spa) 2-6, 2-6, 1-6 (5) Alexander Zverev (Ger), Shelby Rogers (USA) v (6) Petra Kvitova (Cze), (27) Borna Coric (Cro) v Jordan Thompson (Aus)
Court 17
4pm: Christopher Eubanks (USA) & MacKenzie McDonald (USA) 6-7, 2-6 (3) Rajeev Ram (USA) & Joe Salisbury (Gbr), (8) Wesley Koolhof (Ned) v Nikola Metkic (Cro) v Sander Gille (Bel) & Joran Vliegen (Bel), Anna Blinkova (Rus) & Polina Kudermetova (Rus) 6-4, 6-2 (4) Kveta Peschke (Cze) & Demi Schuurs (Ned), Laura Siegemund (Ger) & Vera Zvonareva (Rus) v (2) Elise Mertens (Bel) & Aryna Sabalenka (Blr)
