The A82 is likely to be closed for "some time" following a serious road accident near Luss.
Reports suggest one person has been seriously injured following the incident however this has yet to be confirmed.
The crash, between a minibus and a car, was reported shortly after 3pm today (Friday).
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Police have closed the northbound and southbound carriageways south of Luss.
A police spokeswoman said: "Police were called to a serious road accident on the A82 near Luss at around 2.50pm.
"The incident involves a car and a minibus. Emergency services remain on the scene. The road is closed in both directions."
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According to Traffic Scotland, southbound traffic is facing a lengthy diversion whereas northbound traffic is being sent through the village itself.
Emergency services are still on the scene.
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