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Reuters
Reuters
Business

UK medicine regulator to assess best dose regimen of Oxford/AstraZeneca COVID vaccine

FILE PHOTO: Vials with a sticker reading, "COVID-19 / Coronavirus vaccine / Injection only" and a medical syringe are seen in front of a displayed AstraZeneca logo in this illustration taken October 31, 2020. REUTERS/Dado Ruvic/Illustration/File Photo

Britain's medical regulator will examine all the data from trials of the COVID-19 vaccine developed by Oxford and AstraZeneca, including which dosing regimen is best to use, the regulator's chief executive said on Wednesday.

"Our regulatory review is all encompassing. We will look at all available data," June Raine, chief executive of the Medicines and Healthcare products Regulatory Agency (MHRA), told lawmakers after a study showed the vaccine had efficacy of 62% for trial participants given two full doses, but 90% for a smaller sub-group given a half, then a full dose.

"Clearly, we have great interest into the possible reasons for the different doses having a different efficacy... readout," she said.

"The position is we will look at every piece of evidence... part of that will be to examine with great rigour, the basis for the appropriate dosage regimen."

(Reporting by Alistair Smout, Editing by Paul Sandle)

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