Ty has died of coronavirus, his team has confirmed.
The Mercury Prize-nominated rapper, whose real name was Ben Chijioke, has passed away at the age of 47.
He had been admitted into hospital in early April after showing signs of the bug.
A fundraising page had been set up that said he had been "admitted into the hospital with medical complications related to Covid-19.
"Shortly after, he was put in a medically induced coma to temporarily sedate to help his body receive the appropriate treatment."
The page was last updated on April 19 and suggested Ty was recovering after he was moved out of intensive care.
Ty's shot to fame when he released his debut album The Awkward in 2001.
His second album Upwards was nominated for the 2004 Mercury Prize, which was ultimately won by Franz Ferdinand for their self-titled album.
The musician went on to release three more albums, with the most recent being A Work of Heart in 2018.
Last year he formed a UK hip-hop supergroup called Kingdem with rappers Blak Twang and Rodney P.
He has also collaborated with artists including De La Soul, Soweto Kinch and Roots Manuva.
Many rappers have paid tribute to Ty on social media.
Blak Twang said he was "so numb" as he tweeted a string of broken heart emojis.
Ghetts wrote on Instagram: "RIP TY. This ones deep I had a lot of respect for Ty one of the first from the older generation to embrace me and show me love fly high ty."
"Rest my Brother. You did good," Roots Manuva said.
