Two men were taken to hospital following a stabbing and a street brawl in Rusholme.
Emergency services were called to reports of a fight on Aspinall Street at around 8.45pm on Saturday, April 4.
A man, in his 20s, was found suffering with stab wounds.
He was taken to hospital but has since been discharged.
A short time later police were called to reports of another brawl on nearby Claremont Road.
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Officers detained a 30-year-old man.
He was taken to hospital where he remains.
The man's injuries are not thought to be life-threatening, police said.
Another two men, aged 21 and 36, have been arrested on suspicion of assault.
They both remain in custody for further questioning.
Greater Manchester Police have launched an investigation and are appealing for anyone with further information to get in touch.
A statement said: "At 8.45pm on Saturday, April 4, 2020, police were called to reports of a fight on Aspinall Street, Rusholme.
"Officers attended and found a man in his 20s with stab wounds. He was taken to hospital but has since been discharged.
"A short time later, officers were called to reports of a further disturbance on nearby Claremont Road.
"A 30-year-old man was detained and taken to hospital, where he remains. His injuries are not life-threatening.
"Another two men, aged 21 and 36, were arrested on suspicion of assault. They remain in police custody for questioning.
"An investigation is underway."
Anyone with information should contact police on 0161 856 4409 quoting 2426 of 04/04/20.
Information can also be passed to the independent charity – Crimestoppers, anonymously, on 0800 555 111.
