Trams have been stopped at Victoria after a 'medical emergency'.
Manchester Metrolink has diverted trams away from the station after the incident, thought to have happened at around 2pm.
Tickets are being accepted on bus routes.
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Trams affected include: Rochdale - Monsall, East Didsbury - Etihad, Altrincham - St Peters Square, Bury - Queens Road, Ashton - Picadilly.
Tweeting, Manchester Metrolink said trams are now not running from Bury to Shudehill either.
Replying to somebody called Amber, the company said: "Passengers can use their tickets on the following bus services: 41, 59, 97, 98, 135 408 and 409."
Stagecoach Manchester and Wigan also tweeted to say that tickets were being accepted on route numbers: 43, 85, 86, 101, 103, 142 and 143.
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