Jose Mourinho has welcomed the unfamiliar scenario of a positive selection dilemma in attack, with Tottenham duo Lucas Moura and Dele Alli starting against West Ham after a concussion and one-match ban respectively.
Alli replaces Erik Lamela at no10, while Lucas comes in for Steven Bergwijn despite the latter's brilliant solo goal in Friday's 1-1 draw with Manchester United.
Giovani Lo Celso has recovered from a groin issue to start.
The absence of Juan Foyth (knee) and Japhet Tanganga (back) leaves Mourinho shorter of options in defence, but he has opted against recalling Toby Alderweireld after the Belgian's surprise omission against United.
The visitors' equaliser from the penalty spot aside, Eric Dier and Davinson Sanchez were solid – unusual for a Spurs defence this season – so Mourinho sticks with the duo, particularly as Sanchez's pace will be important against Michail Antonio.
Tottenham XI: Lloris, Aurier, Sanchez, Dier, Davies, Sissoko, Dele Alli, Lucas Moura, Lo Celso, Son, Kane
Subs: Alderweireld, Vertonghen, Winks, Lamela, Sessegnon, Gazzaniga, Bergwijn, Ndombele, Fernandes
West Ham XI: Fabianski, Fredericks, Balbuena, Diop, Cresswell, Noble, Rice, Soucek, Bowen, Antonio, Fornals
Subs: Yarmolenko, Felipe Anderson, Lanzini, Wilshere, Ogbonna, Ajeti, Xande Silva, Randolph, Johnson
Referee: Craig Pawson
