Mauricio Pochettino has not picked an unchanged XI for 93 consecutive matches and on Saturday seems destined to make it 94 against Sheffield United, despite Tottenham's 4-0 win over Red Star Belgrade on Wednesday.
The Argentine is likely to rotate at full-back, despite Serge Aurier’s shaky form and an encouraging outing from Juan Foyth in Serbia.
Fans will be screaming for Giovani Lo Celso to start after a goal on his full debut but Pochettino is determined to be cautious with the Argentine and Christian Eriksen may well return.
Tanguy Ndombele’s progression is further along than Lo Celso’s so the Frenchman has a better chance of keeping his place, but expect Harry Winks to return after being rested for the trip to Belgrade.
Dier’s midweek showing was encouraging but Toby Alderweireld and Davinson Sanchez have begun to form the basis of a partnership in recent weeks.
Jan Vertonghen and Erik Lamela (both thigh) are unlikely to feature. Hugo Lloris has undergone surgery on his elbow injury with a view to returning in January.
Predicted Tottenham XI: Gazzaniga; Aurier, Alderweireld, Sanchez, Davies; Ndombele, Winks; Son, Alli, Eriksen; Kane.
Predict the weekend Premier League results above.
