Jose Mourinho showcased the strength of his Tottenham squad by making eight changes from the 3-3 draw with West Ham, with Gareth Bale's first start of his second stint the most eye-catching selection.
The Welshman is expected to play on the right of a front three after a 20-minute run out against the Hammers.
In years gone by, Harry Kane would probably have had to start this type of game but Mourinho is also able to hand a debut to back-up striker Carlos Vinicius, who was signed for exactly this type of occasion.
In the absence of Eric Dier, Japhet Tanganga and the ineligible Joe Rodon, captain Ben Davies starts at centre-half in a back two and it will be intriguing to see if Mourinho considers the Welshman there in the Premier League, given Spurs' absence of a natural left-sided centre-half.
Tellingly, there is still no place for Dele Alli, with Erik Lamela likely to play no10, and the England international is part of the surely the strongest bench in the club's history, with two goalkeepers, Harry Kane and Heung-min Son also among the 12 subs.
Tottenham XI: Hart, Doherty, Sanchez, Davies (C), Reguilon, Hojbjerg, Winks, Lamela, Bale, Lucas, Vinicius
Subs: Lloris, Austin, Aurier, Alderweireld, Sissoko, Ndombele, Clarke, Lo Celso, Dele, Bergwijn, Son, Kane
