Mauricio Pochettino could easily make 11 changes from Tuesday’s chastening defeat at Colchester, with no fresh injuries in his Tottenham squad for Saturday's Premier League clash against Southampton in north London.
His best option at right-back is still unclear but Serge Aurier should get the nod after encouraging displays in the last two league games.
The manager has urged his players to work harder off the ball and, to that end, he is likely to retain an industrious three-man midfield.
Contract-rebel Christian Eriksen seems unlikely to return to the XI after missing a penalty on Tuesday and Dele Alli did little in Essex to suggest he deserving a start spot ahead of Erik Lamela and Heung-min Son.
The return to fitness of Juan Foyth and Davinson Sanchez allows Pochettino to freshen up his central defence.
As for Southampton, Alex McCarthy is a doubt in goal, while Moussa Djenepo is out with a thigh injury.
Predicted lineups
Tottenham XI: Lloris; Aurier, Alderweireld, Vertonghen, Rose; Winks, Ndombele, Sissoko; Lamela, Son, Kane
Southampton XI: Gunn; Cedric, Danso, Vestergaard, Bertrand; Romeu, Hojbjerg; Boufal, Ward-Prowse; Ings, Redmond
