Jose Mourinho has stuck with the majority of the team that got him off to a winning start as Tottenham manager, by making just one enforced change to the XI started the 3-2 triumph over West Ham on Saturday.
The Portuguese has restored Danny Rose to the starting line-up, with Ben Davies out with an ankle injury, but other than that names an unchanged side for the visit of Olympiacos.
Jan Vertonghen and Tanguy Ndombele are both back from injury but only fit enough for the bench, where they are joined by summer signings Giovanni Lo Celso and Ryan Sessegnon.
Christian Eriksen, whose contract expires next summer, is once again left on the bench, as Dele Alli continues in a central role behind a front three of Harry Kane, Son Heung-Min and Lucas Moura.
With Hugo Lloris and Michel Vorm still out with injury, 20-year-old goalkeeper Brandon Austin is once again named among the substitutes.
Tottenham lineup: Gazzaniga, Aurier, Alderweireld, Sanchez, Rose, Dier, Winks, Dele, Lucas, Son, Kane
Subs: Austin, Vertonghen, Sessegnon, Sissoko, Ndombele, Eriksen, Lo Celso
Olympiacos lineup: Jose Sa, Elabdellaoui, Semedo, Meriah, Tsimikas, Camara, Guilherme, Bouchalakis, Daniel Podence, El Arabi, Giorgos Masouras
Subs: Benzia, Guerrero, Allain, Valbuena, Papadopoulos, Torosidis, Randjelovic
Referee: Georgi Kabakov
