Mauricio Pochettino will welcome back Tanguy Ndombele for Tottenham's London derby clash against Crystal Palace on Saturday.
Record signing Ndombele was back in training this week after a thigh problem and will hope to start for Spurs.
Fellow summer recruit Ryan Sessegnon (hamstring) is available alongside Eric Dier (hip) and Kyle Walker-Peters (hamstring), but Davinson Sanchez is a doubt with an ankle injury.
Argentina internationals Giovani Lo Celso and Juan Foyth are definitely sidelined too with hip and ankle problems respectively.
Crystal Palace boss Roy Hodgson will assess Scott Dann and James McArthur.
Centre-back Dann missed the 1-0 win over Aston Villa with a hand issue but could return, while midfielder McArthur will be checked for an unspecified injury.
Defender Martin Kelly (groin) remains sidelined as does striker Connor Wickham.
Predicted lineups
Spurs XI: Lloris; Walker-Peters, Alderweireld, Vertonghen, Rose; Ndombele, Winks; Son, Eriksen, Dele; Kane
Palace XI: Guaita, Ward, Sakho, Cahill, Van Aanholt; McArthur, Kouyate, Milivojevic, Schlupp; Ayew, Zaha
Provisional squads
Tottenham: Lloris, Gazzaniga, Aurier, Dier, Alderwerield, Vertonghen, Sanchez, Rose, Winks, Sissoko, Wanyama, Eriksen, Skipp, Son, Alli, Lamela, Moura, Kane, Parrott, Ndombele, Sessegnon, Walker-Peters.
Crystal Palace: Guaita, Hennessey, Ward, Cahill, Van Aanholt, Dann, Schlupp, Milivojevic, McArthur, Dann, McCarthy, Camarasa, Meyer, Townsend, Kouyate, Benteke, Ayew, Zaha.
Additional reporting by the Press Association.
