Tottenham will be without a quartet of first-team players when they officially open their new stadium on Wednesday night.
With all the delays and successful pair of test events now in the rear view mirror, out-of-form Spurs, who have picked up just one point from five matches, begin life at the state-of-the-art 62,062-seater venue with a Premier League clash against Crystal Palace.
While every player will no doubt want the chance to further acclimatise to such stellar surroundings, Eric Dier, Serge Aurier, Erik Lamela and Fernando Llorente will all have to wait a little bit longer to play in their first match at the luxurious ground.
England midfielder Dier sustained a hip flexor problem in a Euro 2020 qualifier against the Czech Republic last month, while Aurier limped out of the Ivory Coast's Africa Cup of Nations qualifying tie against Rwanda with a hamstring injury.
Winger Lamela sustained a similar problem before Sunday's last-gasp 2-1 loss to Liverpool and veteran striker Llorente is recovering from concussion.
However, Harry Winks will return to the matchday squad - likely on the bench - after resuming training following his own hip issue.
Mauricio Pochettino has also made it clear that captain Hugo Lloris will lead the club into a new era after his late blunder at Anfield that led directly to Toby Alderweireld's costly own goal.
As for Palace, eight points clear of the drop zone after relegating Huddersfield at the weekend, Mamadou Sakho is the only absentee as he continues to recover from knee surgery.
Predicted line-ups
Tottenham XI (3-4-2-1): Lloris; Alderweireld, Sanchez, Vertonghen; Trippier, Sissoko, Eriksen, Davies; Alli, Son; Kane
Provisional squad: Lloris, Gazzaniga, Trippier, Alderweireld, Vertonghen, Sanchez, Rose, Walker-Peters, Sissoko, Foyth, Lucas, Winks, Wanyama, Skipp, Eriksen, Alli, Son, Kane
Crystal Palace XI (4-3-3): Guaita; Wan-Bissaka, Tomkins, Kelly, Van Aanholt; McArthur, Milivojevic, Kouyate; Schlupp, Batshuayi, Zaha
Provisional squad: Guaita, Hennessey, Speroni, Wan-Bissaka, Ward, Tomkins, Kelly, Van Aanholt, Dann, Souare, Riedewald, Townsend, McArthur, Meyer, Milivojevic, Schlupp, Benteke, Sako, Zaha, Ayew, Batshuayi, Wickham
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